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A muse cell (multi-lineage differentiating stress enduring cell) is a recently discovered non-tumorigenic pluripotent stem cell. They reside in mesenchymal tissues such as bone marrow, dermis and adipose tissue as well as in commercially obtainable mesenchymal cells (human fibroblasts and bone marrow). Muse cells are able to generate cells representative of all three germ layers from a single cell both spontaneously and under cytokine induction. Muse cells do not undergo teratoma formation when transplanted into a host environment in vivo. This can be explained in part by their intrinsically low telomerase activity, eradicating the risk of tumorigenesis through unbridled cell proliferation. == Characteristics == * Pluripotent stem cells, which can generate various kinds of the cells representative of all three germ layers have the ability to self-renew. * Non-tumorigenic. * Exhibit tissue repair effect when supplied to the blood stream. * Can be collected from bone marrow, dermis, adipose tissue and commercially available fibroblasts. * Comprise ~0.03% of bone marrow transplantation and several % of mesenchymal stem cell transplantation. * Can be isolated as cells positive for SSEA-3, a well known human embryonic stem cell marker. * Pluripotent stem cells can be directly obtained from normal human mesenchymal tissues without using artificial manipulations such as gene introduction. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Muse cell」の詳細全文を読む スポンサード リンク
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